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نویسندگان: Ehsaneh Azaryan, Mohammad Yahya Hanafi-Bojd, Sobhan Mortazavi-Derazkola, Esmat Alemzadeh, Fariba Emadian Razavi, Mohsen Naseri

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برچسب: Nanomedicine

کد: GP-91403

خلاصه مقاله: Green synthesis of Hydroxyapatite nanorods using Elaeagnus angustifolia extract for biomedical....

Green synthesis of Hydroxyapatite nanorods using Elaeagnus angustifolia extract for biomedical applications Ehsaneh.Azaryana, Mohammad Yahya Hanafi-Bojda,b,*, Sobhan Mortazavi-Derazkolac, Esmat Alemzadeha,d, Fariba Emadian Razavie, Mohsen Naseri a,* Abstract Aim Hydroxyapatite (HA) is the major inorganic component of natural bone and is commonly used in different biomedical applications. In this study, we reported HA synthesis with a simple way using Elaeagnus Angustifolia (EA) extract as a green model. Methods In order to produce nHA and modified nHA using EA extract without calcination (nHAEA) and with calcination (nHAEA-C) at 800 ◦C for 3 h, sol gel technique was used. The functional groups, structural, morphological and optical features of nanoparticles have been determined using Fourier Transform infrared (FTIR), Xray Diffraction (XRD) and Scanning a transmission electron Microscopy (SEM) with energy dispersive X-ray analysis (EDAX) and transmission electron microscopy (TEM). Results The findings demonstrated that the rod like nHA particles with a length of 61–146 nm and a diameter of 16-29 nm could be fabricated. The presence of HA phase, reported with the XRD and FTIR results. nHAEAs are pure with low crystallite size, needle like, reduced diameter, increased length as well as less agglomerated particles compared with nHA. Conclusions According to the results of this study, nHAEAs are abundant, nutritionally rich and includes biologically active phytochemicals, which can be used in different biomedical applications, such as delivery service for the release of drugs and bone tissue engineering. Keywords: Elaeagnus Angustifolia, Hydroxyapatite, nanorods, biomedical


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