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بدون زمان بندی

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نویسندگان: Sahar Asghari, Matin Mahmoudifard

زمان بندی: بدون زمان بندی

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برچسب: Nanobiotechnology

کد: GP-46790

خلاصه مقاله: According to the increase of deaths due to the metastasis of primary tumors in many cancers, a smart system is required....

According to the increase of deaths due to the metastasis of primary tumors in many cancers, a smart system is required to recognize the initialization of metastasis, immediately and efficiently. In this paper, we use hyaluronic acid-polycaprolactone nanofibrous membranes (NFMs) with a core-shell structure for the efficient capture of circulating tumor cells (CTCs). It’s important to note that the detection of CTC must be specific and accurate to start treatment safely with the correct dose of the drug. Besides, the early detection of cancer and using lower doses of drugs leads to more efficient treatment with lower side effects of drugs, whereas the treatment of secondary tumors require more drug and cost. Our results demonstrated that the cancerous cell capture efficacy using this kind of core-shell NFMs is about 75% (compare to 25% in PCL NFM) which is a significant ratio.


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